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Biotechnology Training Program and Bio-Link
and Todd Smith, Ph.D., Geospiza, Inc.
INTRODUCTION:
The new science of bioinformatics merges biotechnology with the power of computer analysis to reveal new insights and principles in biology. For example, many sophisticated computer programs are now used to analyze DNA and protein sequences. One such program, available free of charge via the Web, is called BLAST (Basic Local Alignment Search Tool). BLAST allows you to compare a known sequence of DNA or protein with other sequences published in nucleotide and protein databases. These comparisons can be vital in understanding the function of a gene, the evolution of a species, or even the identity of a dangerous bacterium. BLAST is maintained by the National Library of Medicine and the National Center for Biotechnology Information (NCBI).
TABLE OF CONTENTS:
This is an animated demonstration of how to use BLAST. It is highly recommended that students view the tutorial before attempting the Hands-On Practice activities.
Two on-line activities for students are presented. Part 1 walks students through using the computer to translate a DNA sequence into a protein sequence. Part 2 challenges students to identify unknown DNA sequences using BLAST. Discussion questions are included.
Bio-Link.orgWeb: www.Bio-Link.org
Email: info@Bio-Link.org
NSF Award #0402139