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The
Double Helix : A Personal Account of the Discovery of the Structure of DNA
James
D. Watson (Author)
List
Price: $14.00
Paperback: 256 pages
Publisher: Touchstone Books; (June 12, 2001)
ISBN: 074321630X
Other
Editions: Hardcover
(Reprint) | Audio
Cassette (Abridged) | All
Editions
This classic biography reads like a detective novel and
like a gossip column. When it was first published in 1968, it was considered
scandalous (and consequently rocketed to the top of the best seller’s
lists). In the book Watson seems to spend an equal amount of time trying to
find a girlfriend and trying to make the biggest scientific discovery of the
twentieth century. Watson wrote so frankly that some of his colleagues
didn't speak to him for years. (His running title of the book had been
“Honest Jim,”). JdK
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Genes,
Girls, and Gamow: After the Double Helix
James
D. Watson
List
Price: $14.00
Paperback: 336 pages
Publisher: Vintage Books; (January 7, 2003)
ISBN: 0375727159
In-Print
Editions: Hardcover
| All
Editions
This new book picks up where the double helix left off and
is written in the same frank and gossipy tone. After discovering the double
helix, Watson moves back to the US to do work at Cal Tech (he trashes California)
and Woods Hole. Along the way he continues his effort that he described in “The Double Helix” to find a girl friend,
aided by other young scientists who later become the scientific elite of the United
States and Great Britain. He describes the early days of the RNA Tie Club
and the efforts involved to work out expression (including the speculation
about and ultimate discovery of the roles of mRNA and tRNA.) It’s an
interesting read. JdK
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What
Mad Pursuit: A Personal View of Scientific Discovery
Francis
Crick
Paperback: 208 pages
Publisher: Basic Books; Reprint edition
(June 1990)
ISBN: 0465091385
Crick’s book was written many years after the discovery of
DNA. Although it’s an interesting book to read, and an important book, it’s
now out of print and hard to find. I guess that the fact that it wasn’t as
sensational and gossipy as “The Double Helix” hurt sales. JdK
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Watson
and DNA: Making a Scientific Revolution
Victor
K. McElheny
List
Price: $27.50
Hardcover: 384 pages
Publisher: Perseus Publishing; (January 7, 2003)
ISBN: 0738203416
In-Print
Editions: Paperback
(Reprint) | All
Editions
An interesting biography that fills in some of the gaps of
the other biographies. It’s especially interesting to read about Watson’s
Harvard days where his colleague E. O. Wilson called him “the Caligula of biology.”
JdK
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Rosalind
Franklin and DNA
Anne
Sayre
List
Price: $13.95
Paperback: 240 pages
Publisher: W.W. Norton & Company;
(July 2000)
ISBN: 0393320448 | All
Editions
Rosalind Franklin died of cancer in 1958 and couldn’t tell
her story. Biographer Sayre, who knew Franklin, wrote this book to counter
Watson’s description of “Rosy”that he gives in his book “The Double Helix.”
Sayre gives voice to this important part of the story. But this biography
has been criticized for going the other way; for lionizing Franklin with an
obvious feminist bias without critically evaluating any of her faults. JdK
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Rosalind
Franklin : The Dark Lady of DNA
Brenda
Maddox (Author)
List
Price: $15.95
Paperback: 416 pages
Publisher: Perennial; (September 30, 2003)
ISBN: 0060985089
In-Print
Editions: Hardcover
(1st) | All
Editions
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Rosalind
Franklin
Cath
Senker
List
Price: $27.14
Library
Binding: 48
pages
Publisher: Raintree/Steck Vaughn; (January
2003)
ISBN: 0739852264 | All
Editions
The two books above are new biographies of Rosalind
Franklin in the same tradition as the Sayre book. They are sympathetic and
draw from her personal correspondence and from interviews with living
scientists including Watson and Crick. But, they also don’t pull punches on
her faults and attitudes (including calling things “so middle class” to
belittle them) and on her inability to get along with others besides Watson
and Wilkins. JdK
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Rivals:
Conflict As the Fuel of Science
Michael
White
Out of
Print
Hardcover: 417 pages
Publisher: Secker & Warburg; (January 1, 2001)
ASIN: 0436204630
Acid Tongues and Tranquil Dreams - Tales of Bitter Rivalry that Fueled the Advancement of Science and Technology As one of its eight
rivalries, this has a section on Watson and Crick versus Linus Pauling versus Franklin and Wilkins. (The others include Newton versus Leibniz for the
discovery of calculus, the U.S. versus the USSR racing to the moon, the Allies versus the Axis racing to develop the atom bomb.) JdK
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A
Passion for DNA: Genes, Genomes, and Society
James
D. Watson, Walter
Gratzer (Introduction), James,
D. Watson
List
Price: $25.00
Hardcover: 250 pages
Publisher: Cold Spring Harbor Laboratory
Press; 1st edition (May
15, 2000)
ISBN: 0879695811
In-Print
Editions: Paperback
| All
Editions
In this collection of essays collected by Cold Spring
Harbor Press, their Director then President Jim Watson writes about the human
genome project, the war on cancer, his early defense of the safety of
recombinant DNA, and other topics in bioethics. On the jacket cover, Richard
Dawkins writes “Jim Watson has elevated his unique combination of justified
arrogance, scurrilous candor, and disconcertingly mature wisdom into an art
form.” JdK
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DNA
Pioneers and Their Legacy
Ulf
Lagerkvist
List
Price: $35.00
Hardcover: 184 pages
Publisher: Yale Univ Pr; (June 1998)
ISBN: 0300071841
This charming book covers the history of biochemistry and
molecular biology. Lagerkvist begins with the earliest alchemists’ view of
science and moves to the present. He includes a scientific biography of the
pioneers of organic and biochemistry including the discovery of DNA by
Frederich Miescher, and the contributions of Emil Fischer and other early
giants. JdK
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The
Eighth Day of Creation: Makers of the Revolution in Biology
Horace
Freeland Judson
List
Price: $42.00
Paperback: 714 pages
Publisher: Cold Spring Harbor Laboratory;
Expanded edition (November 1996)
ISBN: 0879694785
Other
Editions: Hardcover
(Expanded) | All
Editions
This is an excellent book that tells the story of the early
days of molecular biology. It gives the story of the discovery of the
structure of DNA as a play in several acts. But where “The Double Helix”
leaves off, this book picks up; it describes the discovery of messenger RNA
and of the Genetic Code by recounting the stories of the people involved. It
was first printed in 1979, but Cold Spring Harbor Press reissued it in 1996.
JdK
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Invisible
Frontiers: The Race to Synthesize a Human Gene
Stephen
S. Hall, Morgan
Entrekin (Editor)
Hardcover: 334 pages
Publisher: Atlantic Monthly Press; (August
1987)
ASIN: 0871131471
In-Print
Editions: Paperback
| All
Editions
This well written 1987 book went out of print and but thankfully has been rereleased (in paperback) by Oxford University Press. It tells
the early days of the commercialization of recombinant DNA and Genentech and of the effort to produce (and eventually market) human insulin. It has the
same feeling of scientists racing against each other that dominates The Double Helix. But in this case, the race is for the patent on human insulin
and billions of dollars are at stake. The rallying cry of the book and of the competitive industry is “Clone or Die.” JdK
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Making
Pcr: A Story of Biotechnology
Paul
Rabinow
List
Price: $22.50
Hardcover: 198 pages
Publisher: University of Chicago Press (Trd); (May 1996)
ISBN: 0226701468
In-Print
Editions: Paperback
(Reprint) | All
Editions
Rabinow is an anthropologist at UC Berkeley who looks at the people in biotech from the point of view of an anthropologist looking at
a different culture. In this book he turns his attention to PCR. For many people, the discovery of polymerase chain reaction begins and ends with Kary
Mullis’ brainstorm while driving along a winding road on the way to Mendocino. This story fills in the blanks about the team effort at Cetus to
bring this technology to market and into virtually every laboratory. He covers the history of Cetus, from its origin as the first biotech company to
its decline and acquisition by Chiron. Rabinow has also recently written a book that examines the culture of biotechnology in France called “French
DNA.” JdK
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Her-2:
The Making of Herceptin, a Revolutionary Treatment for Breast Cancer
Robert
Bazell, Mary-Claire
King (Introduction)
List
Price: $15.00
Paperback: 240 pages
Publisher: Random House Trade Paperbacks;
(August 1998)
ISBN: 0812991842
In-Print
Editions: Hardcover
| All
Editions
This book recounts the history of discovery of the Her 2
receptor and of the effort, mainly by Dennis Slamon of UCLA, to develop a
monoclonal antibody as a therapeutic drug to treat the cases of breast cancer
that overexpress this antigen. The publisher times the release of this book
with the announcement of Herceptin’s FDA approval. Herceptin will be the
first drug produced at Genentech’s Vacaville manufacturing facility. JdK
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The
Gene Masters: How a New Breed of Scientific Entrepeneurs Raced for the
Biggest Prize in Biology
Ingrid
Wickelgren
List
Price: $26.00
Hardcover: 304 pages
Publisher: Times Books; 1st edition (October 9, 2002)
ISBN: 0805071741
This is one of many books that are now telling the story
of the colorful characters of the Human Genome Project. JdK
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The
Emergence of Bacterial Genetics
Thomas
D. Brock
List
Price: $20.00
Hardcover:
Publisher: Cold Spring Harbor Laboratory; (July 1990)
ISBN: 0879693509
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The
Early Days of Yeast Genetics
Michael
N. Hall (Editor), Patrick
Linder (Editor)
Out of
Print--Limited Availability
Hardcover: 477 pages
Publisher: Cold Spring Harbor Laboratory; (December 1993)
ASIN: 0879693789
These books examine the history of bacterial and yeast
genetics and looks at their importance in triggering the beginning of the
field of molecular genetics. JdK
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For
the Love of Enzymes: The Odyssey of a Biochemist
Arthur
Kornberg
List
Price: $38.00
Hardcover
Publisher: Harvard Univ Pr; (April 1989)
ASIN: 0674307755
In-Print
Editions: Paperback
(Reprint) | All
Editions
Nobel Laureate Arthur Kornberg uses this autobiography to
describe his spectacular career including the discovery of DNA polymerase I
and his pioneering work on DNA replication. He connects his experience with
the earlier scientists in the field. JdK
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