Scientist, Analytical Development
Boston, MA
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Date Posted: |
02/20/09 |
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Date Available: |
02/19/09
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Descriptions: |
Our Client, a Massachusetts based Biotechnology Company that is focused on the research and development of small molecule cancer drugs, is seeking an Analytical Development Scientist.
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Responsibilities: |
Develop and qualify HPLC methods to determine stability and performance of solid and parenteral dosage forms Develop and qualify non-HPLC methods to address other key product performance parameters (e.g., moisture content, dissolution, DSC/TGA) Provide routine and non-routine analytical support (HPLC, DSC/TGA, KF, UV-Vis) for formulation development and in-house formulation/product stability studies Assist in drug product method transfer activities to contract test lab and CMO sites, as needed Manage lab equipment inventories and service contracts Provide day-to-day support for analytical instrumentation maintenance, troubleshooting, and repair; serve as the groups instrumentation expert Author test methods, protocols, and technical reports for a variety of internal analytical activities, including in-house stability studies and dose formulation analysis Work with department manager to develop critical infrastructure systems, including material management, data/information management, lab safety/hygiene management, equipment inventory and service contract management, and other processes that enhance efficiency and productivity Solid experience at independently developing, executing, and troubleshooting HPLC, Karl Fischer, DSC/TGA, and dissolution methods Experience with PSD and XRD methods is desirable.
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Qualifications: |
Knowledge and Skills:
PhD or MS in Analytical Chemistry, Pharmaceutics, or related field
5+ years pharmaceutical industry experience, with core analytical
5+ expertise centered on small molecule solid/parenteral product
5+ development
Strong data organization skills and ability to critically evaluate data trends is crucial for success Previous experience working with contract test labs/CMOs is desirable Familiarity with GLP/GMP processes and regulatory guidelines is preferred Ability to multi-task, prioritize work, and communicate well with team members internally, externally, and cross-functionally.
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Contact Information |
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To Apply: |
Krissy Zambouras
kzambouras@dennispartners.com
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