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Laboratory Notebooks
 Teaching materials
by Linnea Fletcher, Evelyn Goss, Patricia Phelps, and Angela Wheeler
Click here
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An essential activity for working scientists is the maintenance of a daily log in the laboratory notebook. Here is a collection of resources to demonstrate the importance of such documentation as well as practical guidelines for effective notebook organization.
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Biotechnology High School Sharing Day
Curriculum material
Contributions from High School Teachers
Click here
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High School teachers share their favorite Biotechnology activities during the Curriculum sharing day at MATC.
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Biotechnology Book Reviews
Compiled by Bio-Link staff
Click here for link
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Annotated bibliography of useful books related to biotechnology. This project was started by Ji Dekloe, additions and recommendations are welcome.
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Detection of Genetically Modified Food
Teaching materials
Laboratory and classroom activities
Diana Brandner
Madison Area Technical College, Madison, WI
Click here
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Explore Genetically Modified Food Risks, Benefits, Regulation and Detection. Here is a package of teaching materials that includes a wet lab, paper lab and classroom exercises to demonstrate how we detect GMO's in our food. Suitable for advanced High School and two-year College students.
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List of free trade journals and online publications
Online and free resource
Bio-Link staff
Click here for link
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Trade publications and other online resources can be a good way to familiarize yourself and students with industry issues. Included in this list are addresses to contact the publishers.
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Bioinformatics Translation Exercise
Classroom/Computer Exercise
Peggy Maher
Special Projects Coordinator, Biotechnology Austin Community College
Click here
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This exercise uses Biology Workbench, a sequence analysis program found on the web, to look at the difference in normal and sickle-cell hemoglobin. The exercise takes the student through the analysis step by step. The teacher's notes contain background information as well as the answers to the questions.
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Ideas for teaching Biotechnology in the High School
Curriculum Materials
Contributions from High School Teachers
Click here for link
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Here is a collection of teaching ideas collected at the last "High School Biotechnology Curriculum Sharing Day". This page will be updated with new ideas periodically. We are also interested if you have something to share; write us
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Biotechnology Manufacturing Protocols - BT220
Laboratory Exercises
Dr. Sonia Wallman
New Hampshire Community Technical College, Portsmouth, NH
Click here
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This course, offered at New Hampshire Technical College, is an introduction to Industrial Standard Operating Procedures for upstream and downstream processing. The course is designed to provide a hands-on experience exploring the latest techniques of fermentation, purification, and quality control for protein production.
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Overview of Biotechnology at the End of the 20th Century An Introduction to Bioprocessing
Review and On-line resources
Bio-link Staff
New Hampshire Community Technical College, Portsmouth, NH
Click here
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Modern Biotechnology fuses biology with industrial processes. Here are some resources related to bioprocessing and fermentation.
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Center for Engineering Plants for Resistance Against Pathogens (CEPRAP)
Online Resource
Barbara Emberson Soots
Education Coordinator
CEPRAP
University of California, Davis
Click here
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The Center for Engineering Plants for Resistance Against Pathogens at UC Davis is a NSF funded biotechnology education program that serves 45 high school teachers in the greater Sacramento area. This site has many resources available on line such as a plant transformation photo tour, all of our secondary level biotechnology laboratory protocols, and educational software available for free download. The Center focuses on education programs for science teachers, and those groups currently underrepresented in the plant sciences.
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Laboratory Notebooks
Teaching materials
Online resources
Staff
Madison Area Technical College, Madison, WI
Click here
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An essential activity for working scientists is the maintenance of a daily log in the laboratory notebook. Here is a collection of resources to demonstrate the importance of such documentation as well as practical guidelines for effective notebook organization.
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Minitube Immunoblot
Laboratory Exercise
Dr. Karl Roberts
Prince George Community College
Click here
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This laboratory uses an Enzyme Linked Immuno-assay to detect the presence of TMV antigens in tobacco products
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Using RAPD Analysis to Examine Phylogenetic Distance Among Different Plant Species
Laboratory Exercise
Dr. Karl Roberts
Prince George Community College
Click here
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RAPD PCR is used in this laboratory exercise to generate profiles of different types of lettuce. Software that analyzes the band patterns determines the genetic similarity between these species.
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Biotechnology and Bioprocessing Laboratory
Laboratory Exercise
Susan Sharfstein
Assistant Professor of Chemical and Biological Engineering
Rensselaer Polytechnic Institute
Troy, NY 12180-3590
518-276-2166
These materials temporarily unavailable, check back soon or email the author
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This series of laboratory exercises are designed to represent the process by which a biotechnology product is developed and manufactured. The product ß-galactosidase is cloned, grown in fermentors, isolated and analysed.
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Analysis of DMSO using GC-MS
Laboratory Exercise
Mike Solow, PhD
Director of the Northern California Region of Bio-Link
City College of San Francisco
Click here for MS Word file
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Gas Chromotography-Mass Spectrometry (GC-MS) is an analytical instrument used in many laboratory testing situations. Here is a laboratory exercise that explains and uses this methodology to analyse DMSO.
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Pharmaceutical Regulation in the United States: History and a Case Study
Classroom ExerciseText and Discussion Questions
Lisa A. Seidman and Noreen Warren Madison Area Technical College, Madison, WI lseidman@madison.tec.wi.us
Click here for Link
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Drugs are regulated in the United States by the FDA. This exercise reviews the history of some FDA regulations. The Case Study describes the impact one FDA official had by stopping a dangerous drug from coming on the market in the US. A classroom discussion underscores the importance of regulating new drugs.
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Basic Math for Biotechnology Technicians
Math Problem Set
Bio-Link Staff
Madison Area Technical College
Click here for link
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Basic Math is essential for the Laboratory Technician. Here is a series of problem sets that relate Math to the employment skills needed by Biotechnology Laboratory Technicians. Answers are included.
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Tutorials for Excel
Tutorials to Make Teaching Excel Easier
Compiled by Bio-Link
Click here for Link
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Excel is an electronic spreadsheet program that is essential for data organization. Use Excel for data display and graphing.
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Using Interactive Computer Technology to Teach Protein Purification
Computer Classroom Activity
Jeanette Mowery, Biotechnology Laboratory Technician Program, Madison Area Technical College
Click here for link
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This is an introduction to an interactive protein purification computer simulation. The program can be used to teach concepts of protein purification.
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BLAST for Beginners
Classroom Activities
Sandra Porter, Ph.D., Seattle Central Community College Biotechnology Training Program and Bio-Link, and Todd Smith, Ph.D., Geospiza 11/3/00
Click here for Table of Contents
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BLAST (Basic Local Alignment Search Tool) is a powerful computer program that analyzes DNA and protein sequences. It is also a staple of the emerging field of bioinformatics. This collection of materials includes an animated tutorial about BLAST along with on-line activities for students.
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Bioinformatics Tutorials
Online teaching materials
Compiled by the Bio-Link staff 8/6/01
Click here for materials
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Bioinformatics is the science that utilizes computers to analyze biological macromolecules. There are many excellent web sites that explain the use of this computer software and the analysis of these macromolecules. Many of these sites contain educational material and tutorials that are appropriate for classroom use.
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Bioinformatics Links
Online resources
Compiled by Stephanie Tatem Murphy
Click here
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At our recent regional meeting we were fortunate to have Stephanie Tatem Murphy give a brief workshop on Bioinformatics. She passes along some of her favorite web sites.
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Creative Ideas for Teaching Good Manufacturing Practices (GMP)
Classroom & Laboratory Exercises, Intro Text
Madison Area Technical College Staff, Bio-Link Staff, with added contributions by Jim Gerner, Michael Barazia, and Jay Bucher 9/1/00
Click here for a table of contents
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A collection of materials designed to teach students about the federal regulations that apply to pharmaceutical companies
Many of these materials are from the June 2000 GMP Workshops held at the Bio-Link North Central Regional Center
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Wet Corn Milling Lab
Lab Exercise
Eric Olsen, Indian Hills Community College
& Bio-Link Staff 6/6/00
PDF file for Mac or PC
70K download
MS .doc file for PC
75k download
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Wet Corn Milling is an industrial process that that converts corn to a wide variety of by-products. The wet milling industry is the largest non-feed user of corn, using approximately 1 bilion bushels annually. This lab looks at the separation steps in the industrial processing of corn.
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Starch Hydrolysis
Lab Exercise
Bio-Link staff 6/6/00
PDF file for Mac or PC
480K download
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A significant proportion of the cornstarch derived from the wet milled process used for food goes into the fermentation of beer. To be useful to the breweries, it first has to be converted into dextrose or d-glucose. This is an example of down-stream processing; a raw material is isolated and used as a starting material in another process.
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Laboratory Safety Education
Online Resources
Bio-Link staff 8/8/00
Click Here for LInk
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A variety of laboratory safety issues are covered and multiple resources identified such as lab exercises, safety videos, texts and web links
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Biotechnology Books
Book Reviews
Click here for link
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There are many excellent Biotechnology resources in print. Here are reviews of some of the books useful as references and textbooks for the Biotechnology Curriculum.
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Biotechnology Instructional Materials Websites
Online Resources
Bio-Link staff 8/8/00
Click Here for Link
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Check out this list of on-line resources for the Biotechnology educator. Both general interest and specific Biotechnology links are included.
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to this page since 09/19/05.
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